Dysport/Jeuveau/Xeomin/Botox

Dysport, Xeomin, Jeuveau, and Botox all contain the active ingredient botulinum toxin type A neurotoxin that temporarily paralyze muscles to reduce the action that creates deep wrinkles around the forehead, eyes, mouth and neck. Neurotoxins are NOT fillers. They do not replace volume. They are also great treatments for migraine headaches, excess sweating, jaw clenching, TMJ, and tension.

Neurotoxins are the most cost effective options for reduction of wrinkles and reshaping the areas around the eyes and mouth. This treatment option lasts for 3-6 months and offers quick and effective results, taking only 20 minutes per treatment. Typically, you see full result at 14 days, however, most patients see improvement after 72 hours.

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Xeomin vs. Botox®, Dysport®, and Jeuveau®: What’s the Difference?

If you’re considering wrinkle-relaxing injections, you’ve likely heard of Botox®, Dysport®, Jeuveau®, and Xeomin®. All four are FDA-approved neuromodulators that smooth dynamic wrinkles by relaxing targeted facial muscles. But what makes them different—and which one is right for you? Let’s break down Xeomin vs. other neuromodulators so you can make an informed choice.

What Are Neuromodulators?

Neuromodulators are injectable treatments that use botulinum toxin type A to temporarily block communication between nerves and muscles. This reduces the appearance of wrinkles caused by facial expressions, such as:

  • Frown lines (between the brows)

  • Crow’s feet (around the eyes)

  • Forehead lines

  • Smile lines or chin dimpling

What Makes Xeomin Different?

Unlike Botox, Dysport, and Jeuveau, Xeomin is known as the “naked injectable.” Here’s why it stands out:

  • Pure formulation – Xeomin contains only the active ingredient (botulinum toxin A) without added proteins or preservatives.

  • Lower risk of resistance – Some patients build antibodies to other neuromodulators over time, which can make them less effective. Xeomin’s clean formula may reduce this risk.

  • Natural results – Like Botox and others, Xeomin softens wrinkles while allowing you to maintain natural facial expressions.

Xeomin vs. Botox®

  • Similarities: Both are FDA-approved, effective for frown lines, and deliver results within about 3–7 days.

  • Difference: Botox contains protective proteins, while Xeomin does not. For patients who have noticed Botox becoming less effective, Xeomin may be a better option.

Xeomin vs. Dysport®

  • Similarities: Both work quickly (Dysport often kicks in slightly faster) and last about 3–4 months.

  • Difference: Dysport tends to spread more under the skin, making it a good choice for larger treatment areas like the forehead. Xeomin, on the other hand, is more precise—ideal for patients who want highly targeted wrinkle treatment.

Xeomin vs. Jeuveau®

  • Similarities: Both are newer options that work very similarly to Botox.

  • Difference: Jeuveau is often called “Newtox” and marketed to a younger audience at a competitive price point. Xeomin appeals to patients looking for a cleaner, more purified injectable with less risk of resistance.

Which Neuromodulator Is Right for You?

Every patient is different, and the best choice depends on your skin, goals, and prior experience with wrinkle relaxers. Some patients love Botox for its reputation, others prefer Dysport for larger areas, Jeuveau for its affordability, or Xeomin for its pure formulation and reduced risk of resistance.

The good news? All four can deliver smoother, younger-looking skin when administered by an experienced injector.


Man getting injectable treatment